{"id":398,"date":"2019-04-24T10:09:16","date_gmt":"2019-04-24T03:09:16","guid":{"rendered":"https:\/\/vppharmacorp.com\/?p=398"},"modified":"2019-04-25T08:44:48","modified_gmt":"2019-04-25T01:44:48","slug":"so-sanh-nicotinamide-vitamin-b3-voi-clidamycin","status":"publish","type":"post","link":"https:\/\/vppharmacorp.com\/so-sanh-nicotinamide-vitamin-b3-voi-clidamycin\/","title":{"rendered":"So s\u00e1nh Nicotinamide – Vitamin B3 v\u1edbi Clidamycin"},"content":{"rendered":"\n

Nicotinamide (Vitamin B3) v\u1edbi Clidamycin<\/h2>\n\n\n\n

T\u1ed4NG QUAN:<\/strong> <\/h3>\n\n\n\n

Thu\u1ed1c kh\u00e1ng khu\u1ea9n to\u00e0n th\u00e2n v\u00e0 t\u1ea1i ch\u1ed7 c\u00f3 hi\u1ec7u qu\u1ea3 trong \u0111i\u1ec1u tr\u1ecb m\u1ee5n tr\u1ee9ng c\u00e1 vi\u00eam; tuy nhi\u00ean, vi\u1ec7c s\u1eed d\u1ee5ng r\u1ed9ng r\u00e3i kh\u00e1ng sinh ng\u00e0y c\u00e0ng tr\u1edf n\u00ean li\u00ean quan \u0111\u1ebfn s\u1ef1 xu\u1ea5t hi\u1ec7n c\u1ee7a m\u1ea7m b\u1ec7nh kh\u00e1ng thu\u1ed1c<\/strong> g\u00e2y lo ng\u1ea1i v\u1ec1 t\u00ecnh tr\u1ea1ng s\u1eed d\u1ee5ng kh\u00e1ng sinh v\u00e0 l\u00e0m n\u1ed5i b\u1eadt s\u1ef1 c\u1ea7n thi\u1ebft ph\u1ea3i s\u1eed d\u1ee5ng c\u00e1c ch\u1ea5t kh\u00f4ng kh\u00e1ng sinh thay th\u1ebf \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb m\u1ee5n tr\u1ee9ng c\u00e1. Nicotinamide gel<\/strong> cung c\u1ea5p ho\u1ea1t \u0111\u1ed9ng ch\u1ed1ng vi\u00eam m\u1ea1nh m\u1ebd m\u00e0 kh\u00f4ng c\u00f3 nguy c\u01a1 g\u00e2y \u0111\u1ec1 kh\u00e1ng. <\/p>\n\n\n\n

PH\u01af\u01a0NG PH\u00c1P:<\/strong> <\/h4>\n\n\n\n

Trong nghi\u00ean c\u1ee9u m\u00f9 \u0111\u00f4i c\u1ee7a ch\u00fang t\u00f4i, t\u00ednh an to\u00e0n v\u00e0 hi\u1ec7u qu\u1ea3 c\u1ee7a gel 4% Nicotinamide<\/strong> b\u00f4i t\u1ea1i ch\u1ed7 \u0111\u01b0\u1ee3c so s\u00e1nh v\u1edbi gel clindamycin 1%<\/strong> trong \u0111i\u1ec1u tr\u1ecb m\u1ee5n tr\u1ee9ng c\u00e1. 76 b\u1ec7nh nh\u00e2n<\/strong> \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh ng\u1eabu nhi\u00ean s\u1eed d\u1ee5ng gel Nicotinamide 4% (n = 38)<\/strong> ho\u1eb7c gel clindamycin 1% (n = 38)<\/strong> 2 l\u1ea7n\/ ng\u00e0y trong 8 tu\u1ea7n. Hi\u1ec7u qu\u1ea3 \u0111\u01b0\u1ee3c \u0111\u00e1nh gi\u00e1 sau 4 v\u00e0 8 tu\u1ea7n b\u1eb1ng c\u00e1ch s\u1eed d\u1ee5ng \u0111\u00e1nh gi\u00e1 to\u00e0n c\u1ea7u c\u1ee7a b\u00e1c s\u0129, S\u1ed1 l\u01b0\u1ee3ng m\u1ee5n tr\u1ee9ng c\u00e1 v\u00e0 X\u1ebfp h\u1ea1ng m\u1ee9c \u0111\u1ed9 nghi\u00eam tr\u1ecdng c\u1ee7a m\u1ee5n. <\/p>\n\n\n\n

C\u00c1C K\u1ebeT QU\u1ea2:<\/strong> <\/h4>\n\n\n\n

Sau 8 tu\u1ea7n, c\u1ea3 hai ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb \u0111\u1ec1u cho k\u1ebft qu\u1ea3 c\u00f3 l\u1ee3i t\u01b0\u01a1ng \u0111\u01b0\u01a1ng (P = 0,19) trong \u0110\u00e1nh gi\u00e1 To\u00e0n c\u1ea7u c\u1ee7a B\u00e1c s\u0129 v\u1ec1 Vi\u00eam m\u1ee5n: <\/p>\n\n\n\n

– 82% b\u1ec7nh nh\u00e2n \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb b\u1eb1ng gel\nNicotinamide<\/strong> v\u00e0 68% \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb b\u1eb1ng gel\nclindamycin<\/strong> \u0111\u00e3 \u0111\u01b0\u1ee3c c\u1ea3i thi\u1ec7n. <\/p>\n\n\n\n

– C\u1ea3 hai ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb \u0111\u1ec1u t\u1ea1o ra s\u1ef1 gi\u1ea3m t\u01b0\u01a1ng t\u1ef1 v\u1ec1 m\u1eb7t t\u1ed5n\nth\u01b0\u01a1ng do m\u1ee5n (s\u1ea9n \/ m\u1ee5n m\u1ee7; -60%  Nicotinamide<\/strong> so v\u1edbi -43%<\/strong> clindamycin<\/strong>, P =\n0.168) v\u00e0 m\u1ee9c \u0111\u1ed9 nghi\u00eam tr\u1ecdng c\u1ee7a m\u1ee5n tr\u1ee9ng c\u00e1 = 0.161). <\/p>\n\n\n\n

K\u1ebeT LU\u1eacN:<\/strong> <\/h4>\n\n\n\n

Nh\u1eefng d\u1eef li\u1ec7u n\u00e0y ch\u1ee9ng minh r\u1eb1ng gel 4% Nicotinamide<\/strong> c\u00f3 hi\u1ec7u qu\u1ea3 t\u01b0\u01a1ng \u0111\u01b0\u01a1ng v\u1edbi 1% gel clindamycin<\/strong> trong \u0111i\u1ec1u tr\u1ecb m\u1ee5n tr\u1ee9ng c\u00e1. <\/p>\n\n\n\n